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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1ed1c2a79805ae8be9375ac05d0e109d71f1390a53e568c7c1fdcf6bd5342490' 
  AND token = 'aIhvzUZMPxwhG42OBUNaAv+6nillktRV+A4wawz0ITA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}