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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1dfcd70788857c41dc60390f4557ca6d82ea9abf9dec45cce37d38552c6f64b4' 
  AND token = 'd0ZCe1Twb/IIDb86OMuyIWFRhTqU8gc5E6vUvkj3YqE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}