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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'afb08848ce477955e58b5824c314c7a9a3bcf38222f89c2d5bfd49b4c472edb4' 
  AND token = 'Unp2Cv36pJJA6QTBycRKcy7EYZ7vTaFT3jNdIEAXbRM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}