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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '723d12924f03001c68bdf549dcb336abbe1402897dcaa3367dd38be427e92ef3' 
  AND token = 'Xru3tMZzvHcIEmUQYCFGQtiQQM7CBEgiQ8QmwNUa7Bk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}