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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4885b8520f4c4af296032b4cd6505695509bc55b0540e397500ba9e2cbabba77' 
  AND token = 'Eqwo6RtlRGsMknJbpYKVonTAW+TMgldUZ7KK+rBHx/c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}