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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b22a94cd7b7f676eb72566f9204c2385c36fb43c99dd74da6b59b6728ccfd68d' 
  AND token = 'WtZxgw12TdYaCdKWnP1t87UH4L8BonEBamiy3buKWfw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}