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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '48e7d14a8b4f4f3a7a93ebffd7ed1adf0a98e7e3c098c08d3f1cffbe74cb0142' 
  AND token = 'hmKf0oK/VQ+SgkOkGvVMlTdhXopo+Gyd3NHUksZUv3s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}