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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e585cd71f06dd7154d9e0d75baf2a5caeba1f8da6e9f3e028e2c485d98513b7d' 
  AND token = 'eit+JP2G+MfB9ITo6B1qxv+rQB74LoZAQgrKpc+uB/0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}