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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8bbf249bd381b35d5bb9ffbb63851945ba56bffce31948d384eb7094b081b849' 
  AND token = 'BZ/s+J6Og+Hd5JPVDIY6OtO3R0cJxKmt5Q6yq2BiUOI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}