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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'de046b806958977fc927f272e64f85f91847ce8bc3cb17ac9608c63f4c7d878b' 
  AND token = 'slQf/YA+/Im82mnfCoemyAaIarTZLcA5OZW3A1APC3E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}