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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2e09ef5801ecf49b3dc2023f2db1720f656889237ed3e49b27c64589060db4c0' 
  AND token = 'svc5dJsR+PE5W35qHfMyO/itguhsKrftWxLdo45ZyBg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}