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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5987a75b07f0935bff52d4dd44b7dd80d69c8552050df54077cfb78880607d1d' 
  AND token = 'JhZk16zXfy0h+I+muFAPVCYFwin4CH2keNojuzyiLF8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}