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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c6fc74cd32d30eb83c807054340b1c6aad8191f88511b6e4601c4e3ebc3942cd' 
  AND token = 'n+iB6w5kXoO/u987qEjjHMrsPT4Zq81bzFYdOLFEgLY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}