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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0c3f60ea91f8c1f6dbca1b35fa9c18279d22b3ea4e0257274aa5f0be25e41913' 
  AND token = 'ePl1VneRhRArvRLTAUvCFUmODuXVNAf7cGBXdyZ22GM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}