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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '178defefa5231917d0a0a4f9a3300231bbfcaa4efd2a0760702bfb7d5aaad6f2' 
  AND token = '9aQwTAQMofL70Z5u6RkTbnEusSxYAMvoTdXX+xsM/vc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00014

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}