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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c41c7445d244e4a73e8327e29d3ed8d06283c8daa292e09958589c9ca3f40130' 
  AND token = 'ETVrQBAWgvSmbHwLGg8T3j2yiEYvY9pxIWTsOUg5qU4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}