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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '416deeca6bee86b992ffbe795cb670336014e9fe5b8543f4fff2349a2b8a0c6f' 
  AND token = '2es5cBuRaaaVSFK3m/Tb9qMY1gUSU+iiOF+ofEqntSA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}