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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9cf835db3249d0c9d2b4451206cfedfee2422ae3141b86d8e8f3cb692c0a7de7' 
  AND token = 'JGgzTFxS7nga6kAJFLGWOuVyxHDeR9NSaAo23mFFWuU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}