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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '389fa6505ee9ddb6701a4d6f2a2e571dc3367eed624e2115d85c8b8f9d218d67' 
  AND token = 'mVf0QYWF0g+xbaOArTd5qQz9GRtha/oexTBunm+bNpA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}