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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3b8f6f1eba3c0b5ff74dd0476f810456160413bcc098f2c3f5f29845af3c4cbb' 
  AND token = 'HWPfCXII0n0QIlM2+5viHATUldxE2pFmZCx7mBDU2rg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}