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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3123519c19abf7eb73049a5fa4cfed36a4aea394e2fb60f41eb9024b96ca7a56' 
  AND token = 'CwrVFb79UaPWTLTE8/sbWUPkWoAT0IXUh877aPSY+y0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}