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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '332a83bb4894e07bfb7251453251d3a9caa620c9331b0a3b195151f2e3e762c3' 
  AND token = 'VaudeP+Ny7wPpBC+i0VtHKhLLll6XgpOF+UWFf5kdLc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}