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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '386dcd3fa16543b0b4126d00481c3b57c238ab90c403d30d19e923b9c83755a2' 
  AND token = '/sZsfKbpWNEWFxTpbB4E/lLK4rFsm34F/ZV63XQ9gg4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}