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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5e0b19edc34db0a608425a39fce30c9229be64cd265a637fd002d4b63adb0581' 
  AND token = 'DlY1KMifp+PfCKy2I3t4TQ7DWh1jDEWaut2QGSYP6U4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}