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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cb69153c38b434ca65fb48f6d3314b4e98c5a27295306e4559679b3af774838a' 
  AND token = 'sTYxFDYBnEJvnc/budTBLdS7hoqznkUFoZl1a4fup4A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}