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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5f0c6b864dbd21a574bee74725fa00a0a1074c3e8efdad705b6d251d8d8b0f5d' 
  AND token = 'WijXj4faPMJANS0RnQ3qLt/aL3Re74XEFDYfih2vbgQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}