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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3dc5d7a9390dd12944c3b9b3946096b607e6cf49b64f6dbcf3c1f250376c7a79' 
  AND token = 'OG0HBgxZICadTAngLA3mWJwKjNSgZNOJb2QNUxsmNg8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}