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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8217e83d0fdc378dbaebd8b78b6d2de94323e974e1b6314e0f328c38e2abd31c' 
  AND token = 'Tg6ZQ7/HX3WWd6rDytM8P0vC+CIjCy4zVJZ3EEcPbmw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}