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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c05e500c6b0b06f555d6b9021e67e606c187dcfc636f2ec641febdbf7082c47e' 
  AND token = 'y05V4Ta62jMf7t+Lzn29Q+GyE/eS42jEeK7t4obVmJc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}