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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '51459cec3410c0f6b7bf88dcac478a1cd966d7e54b329b0a9181bf0fcce5b5f9' 
  AND token = '6TY3Wkn3TNeu4H+dvlMyRZQnm91kH+9JyoSOf7LGBMs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}