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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4f843ffcc4b10e2d26666483ec6a7fa900e91a8a9dfb2185dbe6ef123d723a38' 
  AND token = 'CWM1Py4LZ2lFvn1zrVVTrkVOBlZJTFMVGWL6+MtGrMI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}