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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f685410ec1624b5aa9dda7cf32f0d178929b04f86f1c00e86d71e6300c60db55' 
  AND token = 'ptH3sKQR68WVcraZVwt4jGKtz2DLH/ce5Kk8x7kayoI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}