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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1505312f7d52e52a024de256d9e6e27aec1135675e4f1c94593105bbe0327e4b' 
  AND token = 'K9+9f/iFQwNKUSMZZ4el9mQNRO8G8d4VkG0HdeYlBtM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}