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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a75c9c487b1884a50ced8f43a1f868a239760318bb5613bc5a80453d63cc2188' 
  AND token = 'Tz+OCH1t2Cq3ERO4pZ4pCZpL5D9mcmktFaowNLpn93o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}