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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1b6154cc8d384a22f529bca40ad714b9ceea4da81c9d8e99e558b3907b52586b' 
  AND token = 'mJpOfymqcu34kQQ852WVX7IKaYUnKZsQeALegAdBQYk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}