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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a5c26ae31fa829d8046021b1fccc47d83a6262df338f4bc5071a85efadde4426' 
  AND token = '971LXOEKh7epyW4vI0a06j9eTAVttMutBFH9Ta0Oys4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}