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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a5582f75ad49862ffff1b539abaf7b7e2ee9432d20d8c20d65f6abf99bbe0a89' 
  AND token = 'CxWuthb/SstyIvacdnAdLlhBFDc0WX6FX6UDwincG0I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}