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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4897ea3170d15e53a63b8a94c9e745070f89de88f2c4536b8dfd7f3285502681' 
  AND token = 'EYdr+Wz+B0JIQh+mWZ/uiheWmeYqAahBsNOzieOW3F4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}