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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5c20d147f135b6fd49c2b050eceee9849cb1ac25b6b14d42247d6e1b05229b1a' 
  AND token = 'rfhxMH5zyXPHTL+2IWC8N7hnD7BPJJHOP7SMxQ+udUU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}