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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2eff5bd0f31e2cbc6fd92429b75f4844d7c83ff03826c0655a8831d92405344d' 
  AND token = 'W4Y+8oS2LxU0oOKboDj48g6W4o/UAK4iOS4NKAkPzEI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}