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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '95b665866cb42642b730147bd2038133944fd211ea649497886da051401b7e1e' 
  AND token = 'thega1WkoTO9r7cyWOu/NCiVda6iuVmXwS2Xipq7LZw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}