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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1e5b2b02a50760c385aa1641a90a213c27de5ccea92976296ce87e286392a2d4' 
  AND token = '9hoWOWXnjzr+CCtva3/BU+j7vuGY0KlqsMkv7PsQBE8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}