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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e45d81e45db32f324650e17dd757515e98a254e65c8a02d51e2d2bf69aca9b3b' 
  AND token = 'KlKVlLLj4my9SkzonqN2G1YuMDEDehjFXnr8BITIjT4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}