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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8924f091bf34348265a900f7d1814c101a2b0d73a78c86efe3e2eebccbe79dde' 
  AND token = 'BpUpthXMjm640+FcWeOCxR52nFA4n+dEHMMBLKUS7FU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}