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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '22b4a5059aaf15033f4357c4058f9ec3049aca5d140aad830e7981cba43bd564' 
  AND token = 'l8hxQt+0gfeX2XCm7bJ+Et1CXaZJpGznhZ3Lk+dw094=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}