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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'eaa4c0e5a7434c99e92831ec55b9b104900346d7e48564e5567181f62505f37d' 
  AND token = 'RmAPKu5VlNQxmmB3Gb2UCM1Aknd3DFPI9tFi0pZUToI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}