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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8e76942bb4b1b1280459bad25b05358910c2f0a0852f242b9836990296c8dd95' 
  AND token = 'RcT+SdFspu3tJsHMRLUO+BfpM1Pxus+E+adsdvFyDc4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}