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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ea86d93092f85082bf8f08f3ecb4eb8facb007327611bb06fd94171f530d3e97' 
  AND token = 'rLdNE5zYILtmsRSUhBMXze19YZaSEO/H2lJzWcj2kUs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}