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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8a9bf4c37e4827aa2ccad98cb9ec053ecf986b1be0bf72fc89d7ad3ae90dd525' 
  AND token = '24y+JstK+oLew4emfDVzK2qVXmczsWx+DDwkGU+CVRs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}