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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '95e85561ba9450c74cabb8c739b85a0648411e85f16be2283354f73ae3e674a2' 
  AND token = 'ERTlaS1xSLt1V1weziGbGA7dl/IB3vQvLNjHUOgLG7Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}